Viscosupplementation

9%

Improve with treatment

40%

Improve with control

51%

Do not Improve

What does improve mean?

An example of a 30% reduction in pain scores is a decrease from 6 to 4 on a 10 point pain scale

0
1
2
3
4
5
6
7
8
9
10

How many people will improve?

49%

Improvement by treatment or placebo

51%

No Improvement

Viscosupplementation Harms

Serious Adverse Events
11.5%
13.5% (placebo)
Treatment Related Adverse Events (After 1 Injection)
29.9%
27.9% (placebo)

Other Considerations

  • Efficacy is similar to placebo in trials without industry funding.
  • Approximate cost (CAD) for 1 Injection for the Knee: $400-$500

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Osteoarthritis Pain

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