NSAIDs (Oral)
18%
Improve with treatment
40%
Improve with control
42%
Do not Improve
What does improve mean?
An example of a 30% reduction in pain scores is a decrease from 6 to 4 on a 10 point pain scale
0
1
2
3
4
5
6
7
8
9
10
How many people will improve?
58%
Improvement by treatment or placebo
42%
No Improvement
NSAIDs (Oral) Harms
Withdrawals due to Adverse Events
5.6%
5.7% (placebo)
Other Considerations
- Consider naproxen or ibuprofen. Diclofenac and COX-2 inhibitors (celecoxib) may increase cardiovascular risk.
-
Approximate cost (CAD) for 30-day supply:
Naproxen $15-30, Celexcoib $20-30

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Osteoarthritis Pain
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