Acetaminophen

0%

Improve with treatment

40%

Improve with control

60%

Do not Improve

What does improve mean?

An example of a 30% reduction in pain scores is a decrease from 6 to 4 on a 10 point pain scale

0
1
2
3
4
5
6
7
8
9
10

How many people will improve?

40%

Improvement by treatment or placebo

60%

No Improvement

Acetaminophen Harms

Withdrawal due to Adverse Events
7.4%
6.5% (placebo)
Abnormal Liver Function (Hepatic Enzyme 1.5x UL)
6.6%
1.8% (placebo)

Other Considerations

  • Most trials studied a dose of acetaminophen 1000mg every 6 hours
  • Approximate cost (CAD) depends on place purchased, 150 tablets for ~$10

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Osteoarthritis Pain

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