NSAIDs (Topical)
11%
Improve with treatment
40%
Improve with control
49%
Do not Improve
What does improve mean?
An example of a 30% reduction in pain scores is a decrease from 6 to 4 on a 10 point pain scale
0
1
2
3
4
5
6
7
8
9
10
How many people will improve?
51%
Improvement by treatment or placebo
49%
No Improvement
NSAIDs (Topical) Harms
Withdrawal due to Adverse Events
Gastrointestinal Adverse Events
Local Site Reactions
Other Considerations
- Data unavailable to support one formulation or concentration over another.
- Approximate cost (CAD) for over-the-counter Diclofenac 1.12% , 100g for ~$15
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Osteoarthritis Pain
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