SNRIs (Duloxetine)
21%
Improve with treatment
40%
Improve with control
39%
Do not Improve
What does improve mean?
An example of a 30% reduction in pain scores is a decrease from 6 to 4 on a 10 point pain scale
0
1
2
3
4
5
6
7
8
9
10
How many people will improve?
61%
Improvement by treatment or placebo
39%
No Improvement
SNRIs (Duloxetine) Harms
Withdrawal due to Adverse Events
12.4%
5.5% (placebo)
Gastrointestinal Adverse Events
35.5%
7.7% (placebo)
Serious Adverse Events
1.1%
1.2% (placebo)
Other Considerations
- Approximate cost (CAD) based on lowest dose, 30-day supply: $40 to $50

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