SNRIs (Duloxetine)

21%

Improve with treatment

40%

Improve with control

39%

Do not Improve

What does improve mean?

An example of a 30% reduction in pain scores is a decrease from 6 to 4 on a 10 point pain scale

0
1
2
3
4
5
6
7
8
9
10

How many people will improve?

61%

Improvement by treatment or placebo

39%

No Improvement

SNRIs (Duloxetine) Harms

Withdrawal due to Adverse Events
12.4%
5.5% (placebo)
Gastrointestinal Adverse Events
35.5%
7.7% (placebo)
Serious Adverse Events
1.1%
1.2% (placebo)

Other Considerations

  • Approximate cost (CAD) based on lowest dose, 30-day supply: $40 to $50

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