Opioids

6%

Improve with treatment

40%

Improve with control

54%

Do not Improve

What does improve mean?

An example of a 30% reduction in pain scores is a decrease from 6 to 4 on a 10 point pain scale

0
1
2
3
4
5
6
7
8
9
10

How many people will improve?

46%

Improvement by treatment or placebo

54%

No Improvement

Opioids Harms

Withdrawals due to Adverse Events (Any Opioid)
25.9%
7% (placebo)
Nausea
25.9%
8.2% (placebo)
Constipation
16.2%
5.3% (placebo)
Dizziness
15.1%
5.6% (placebo)
Drowsiness
15%
4.2% (placebo)
Headache
8.6%
7.8% (placebo)

Other Considerations

  • Last option due to risk of dependence, side-effects, and long-term serious harms
  • If absolutely needed, doses should be kept ≤ 90 mg/day of morphine equivalents
  • Should be used short-term
  • Side effects are more common in older patients and may lead to falls
  • Approximate cost (CAD) depends on opioid used, 30-day supply: $20+

Looking for further details?

Osteoarthritis Pain

Why doesn’t this calculator cover all treatment options available?

This online calculator does not cover all treatment options available for osteoarthritis pain. We only included the medication treatments that had the highest quality evidence. A healthcare provider may consider other options not listed in this calculator to manage symptoms, depending on specific needs.

Where can I find the evidence used to create this calculator?

The data used for this calculator can be found within the Osteoarthritis Umbrella Systematic Review

Additional tools created with this data can be found at Osteoarthritis Decision Aid